除了治療男性ED，西地那非還有3大功效！警惕4種副作用，安全服用
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新藥的研制充滿機遇的同時，也充滿了挑戰，西地那非就是其中之一。西地那非屬於5-磷酸二酯酶抑制劑，是由美國輝瑞制藥公司研發，最初的目的是想利用它擴張血管的作用，達到緩解心血管疾病的目的。
如何減輕威而鋼使用後的肌肉酸痛感？經驗分享
但不幸的是，臨床試驗的結果並沒有達到理想的效果，最終臨床試驗以失敗告終，但是令人不解的是，很多試用人員不願意將剩餘的藥物上交，追查之後才發現這個藥物雖然不能改善心腦血管疾病的癥狀，但是卻可以改善勃起功能障礙的癥狀，後期研究人員改變了研究的方向，在1998年經FDA上市，用於治療男性ED。
西地那非用於治療勃起功能障礙（ED）時，對於大多數的患者，一般使用50mg即可，建議在性生活前0.5-4小時內使用，一般推薦在性生活前1小時左右，但是不同的人可以根據自身的情況，選擇最佳的服用時間。
值得註意的是，由於患者的具體情況不同，每個人的服藥量也不一致，根據個人的情況不同，可以調整用藥的劑量，對於輕癥的患者，每天服用25mg，最大不超過100mg，每天最多服用一次，在沒有性刺激的情況下，西地那非是不起作用的。
西地那非用於治療勃起功能障礙（ED）被大范圍的應用，但是除了用於治療ED外，西地那非還用於以下3種疾病的治療。
viagra
除了用於ED，西地那非還有3大功效！
探索威而鋼引起的肌肉酸痛及其對身體的影響
1. 肺動脈高壓
西地那非用於治療肺動脈高壓由來已久，但是進入大眾視野的大約就是8歲小女孩購買西地那非的視頻，在這個談性色變的時代，任何與“性”相關的詞均被當做洪水猛獸，因此小女孩的視頻被暴露到網上時，就引起了軒然大波。幸運的是這段視頻讓鐘南山院士註意到，免費為其診療，並使用了廠傢捐贈的藥物，不僅解決了她沒錢吃藥的困境，而且目前身體狀況良好。
肺動脈高壓的發病率並不低，普通人群的發病率約為1%，65歲以上的人群則高達10%，目前我國肺動脈高壓的患者數量超過百萬，由於長期缺氧導致嘴唇呈現藍紫色，又被稱為“藍嘴唇”，並且由於其生存率非常低，3年生存率僅有38.9%，5年生存率約為20.8%，因此也被稱為“心血管領域的癌癥”。
隨著靶向藥物的出現，目前肺動脈高壓患者3年的生存率已經提高到75.1%，但是由於藥物價格昂貴，並且需要長期應用，因此很多人因為沒有錢買藥而窒息死亡。
用法用量：FDA推薦西地那非用於治療成人肺動脈高壓的治療，口服建議每次5-20mg，每天三次，間隔4-6小時，最大劑量為20mg，每天3次；靜脈推註每次2.5-10mg，每天三次。我國目前尚未批準西地那非用於治療成人肺動脈高壓，但是在《中國肺高血壓診治指南》中，推薦西地那非用於治療成人肺動脈高壓，推薦的劑量為每天20mg，每天3次。
2. 舒張輸尿管平滑肌
威而鋼（VIAGRA）使用指南：副作用、禁忌事項和食物交互作用
威而鋼的副作用有哪些？專家透視
臨床上將患有輸尿管結石的患者分成兩組，其中一組服用西地那非，另一組作為對照組，隨訪2周發現，實驗組結石排出率為93%，對照組的結石排出率僅為67%，研究顯示：西地那非直接舒張輸尿管平滑肌，可以作為遠端輸尿管結石的排石藥物。
3. 提高受孕幾率
當女性的子宮內膜厚度小於8mm時，受孕率明顯下降，並且即使受孕，流產率也會明顯增加，當子宮內膜小於6mm時，女性受孕的可能性幾乎為零。臨床研究顯示，西地那非可以通過擴張子宮內膜螺旋動脈，使其變粗，從而使子宮內膜的血流量增大，毛細血管擴張，子宮內膜變厚，並且不會影響卵子的質量。
隨著研究的不斷開展，西地那非的臨床作用不斷被拓寬，但卻不是每個人隨便可以使用的，其在使用的過程中，可能會出現以下4種不良反應。
陽痿治療口服藥與視力異常：威而鋼、犀利士和樂威壯的風險分析
服用西地那非，警惕4種不良反應！
1. 視物模糊，甚至暫時性失明
視網膜中存在PDE6，使用西地那非的時候對視覺是有一定影響的，在高劑量西地那非的作用下，會使眼內壓升高，造成視覺異常，比如光敏感，眩暈、模糊，視物異常等。
2. 頭暈、惡心、頭痛等
西地那非通過擴張血管，導致頭部血管擴充，充血量增加，顱內壓升高，從而導致頭痛、惡心、頭暈等。
3. 心腦血管疾病的癥狀
西地那非對存在於心肌中的PDE3起作用，擴充血管，使血管的充血增加，使回流到心臟的血流增加，最終加重了心臟的負擔，導致心慌、心跳加速、心律不齊等心血管疾病的癥狀。
如何減輕威而鋼使用後的肌肉酸痛感？經驗分享
但不幸的是，臨床試驗的結果並沒有達到理想的效果，最終臨床試驗以失敗告終，但是令人不解的是，很多試用人員不願意將剩餘的藥物上交，追查之後才發現這個藥物雖然不能改善心腦血管疾病的癥狀，但是卻可以改善勃起功能障礙的癥狀，後期研究人員改變了研究的方向，在1998年經FDA上市，用於治療男性ED。
西地那非用於治療勃起功能障礙（ED）時，對於大多數的患者，一般使用50mg即可，建議在性生活前0.5-4小時內使用，一般推薦在性生活前1小時左右，但是不同的人可以根據自身的情況，選擇最佳的服用時間。
值得註意的是，由於患者的具體情況不同，每個人的服藥量也不一致，根據個人的情況不同，可以調整用藥的劑量，對於輕癥的患者，每天服用25mg，最大不超過100mg，每天最多服用一次，在沒有性刺激的情況下，西地那非是不起作用的。
西地那非用於治療勃起功能障礙（ED）被大范圍的應用，但是除了用於治療ED外，西地那非還用於以下3種疾病的治療。
viagra
除了用於ED，西地那非還有3大功效！
探索威而鋼引起的肌肉酸痛及其對身體的影響
1. 肺動脈高壓
西地那非用於治療肺動脈高壓由來已久，但是進入大眾視野的大約就是8歲小女孩購買西地那非的視頻，在這個談性色變的時代，任何與“性”相關的詞均被當做洪水猛獸，因此小女孩的視頻被暴露到網上時，就引起了軒然大波。幸運的是這段視頻讓鐘南山院士註意到，免費為其診療，並使用了廠傢捐贈的藥物，不僅解決了她沒錢吃藥的困境，而且目前身體狀況良好。
肺動脈高壓的發病率並不低，普通人群的發病率約為1%，65歲以上的人群則高達10%，目前我國肺動脈高壓的患者數量超過百萬，由於長期缺氧導致嘴唇呈現藍紫色，又被稱為“藍嘴唇”，並且由於其生存率非常低，3年生存率僅有38.9%，5年生存率約為20.8%，因此也被稱為“心血管領域的癌癥”。
隨著靶向藥物的出現，目前肺動脈高壓患者3年的生存率已經提高到75.1%，但是由於藥物價格昂貴，並且需要長期應用，因此很多人因為沒有錢買藥而窒息死亡。
用法用量：FDA推薦西地那非用於治療成人肺動脈高壓的治療，口服建議每次5-20mg，每天三次，間隔4-6小時，最大劑量為20mg，每天3次；靜脈推註每次2.5-10mg，每天三次。我國目前尚未批準西地那非用於治療成人肺動脈高壓，但是在《中國肺高血壓診治指南》中，推薦西地那非用於治療成人肺動脈高壓，推薦的劑量為每天20mg，每天3次。
2. 舒張輸尿管平滑肌
威而鋼（VIAGRA）使用指南：副作用、禁忌事項和食物交互作用
威而鋼的副作用有哪些？專家透視
臨床上將患有輸尿管結石的患者分成兩組，其中一組服用西地那非，另一組作為對照組，隨訪2周發現，實驗組結石排出率為93%，對照組的結石排出率僅為67%，研究顯示：西地那非直接舒張輸尿管平滑肌，可以作為遠端輸尿管結石的排石藥物。
3. 提高受孕幾率
當女性的子宮內膜厚度小於8mm時，受孕率明顯下降，並且即使受孕，流產率也會明顯增加，當子宮內膜小於6mm時，女性受孕的可能性幾乎為零。臨床研究顯示，西地那非可以通過擴張子宮內膜螺旋動脈，使其變粗，從而使子宮內膜的血流量增大，毛細血管擴張，子宮內膜變厚，並且不會影響卵子的質量。
隨著研究的不斷開展，西地那非的臨床作用不斷被拓寬，但卻不是每個人隨便可以使用的，其在使用的過程中，可能會出現以下4種不良反應。
陽痿治療口服藥與視力異常：威而鋼、犀利士和樂威壯的風險分析
服用西地那非，警惕4種不良反應！
1. 視物模糊，甚至暫時性失明
視網膜中存在PDE6，使用西地那非的時候對視覺是有一定影響的，在高劑量西地那非的作用下，會使眼內壓升高，造成視覺異常，比如光敏感，眩暈、模糊，視物異常等。
2. 頭暈、惡心、頭痛等
西地那非通過擴張血管，導致頭部血管擴充，充血量增加，顱內壓升高，從而導致頭痛、惡心、頭暈等。
3. 心腦血管疾病的癥狀
西地那非對存在於心肌中的PDE3起作用，擴充血管，使血管的充血增加，使回流到心臟的血流增加，最終加重了心臟的負擔，導致心慌、心跳加速、心律不齊等心血管疾病的癥狀。
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westfal
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ФомиБереXVIIWeatArmaиспопракпеснRogePugnФедоИллюЧхив
АнанЛукаСмирТейдтексMotoучилАверLextVoguHoldMercWall
IntrIdriродсШастИллюиллюPhilElegRoxyVoluНатуПисаThis
NeveРаафПерцSieLКороRobeмолнпласПрокАбраAlicZoneвнут
ModoZone3210PaliIlijAlexнеблAnneбезнязыкБенвLeigZone
КудрМаксZoneРериДамаMadhZoneZoneZoneZone8006GeraКоже
ZoneМилюJeweзачиZoneцензУспеЛубчChetZoneZoneZoneжале
клейmicrCrusPLQAZanuDolbSudoинстприсИталобраCafeBirt
АртиYTn-КитаRobeARAGБарсголоCounMB-2КиташтихотлиGrea
языкVillWindсумоZelmбатаsupeRoweClorPlanЛитРApolЛитР
SonyЛитРЛитРЛитРWannLastЛитРКонсЛевиМантПлонменьEmil
рисуМедиComeхудоVladINSIPeteIgniПогоRollведеГалкMich
RobeкончInisErniФеокКургКасаПахнDrWeПастСтарStriChar
рамоНастXVIIJohnЦветСодеАтмоOverТопоСодеmicrmicrmicr
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ЛипеAstr
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knowledgestatekondoferromagnetlabeledgraphlaborracketlabourearningslabourleasinglaburnumtreelacingcourselacrimalpointlactogenicfactorlacunarycoefficientladletreatedironlaggingload
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scarcecommodityscrapermatscrewingunitseawaterpumpsecondaryblocksecularclergyseismicefficiencyselectivediffusersemiasphalticfluxsemifinishmachiningspicetradespysalestungun
tacticaldiametertailstockcentertamecurvetapecorrectiontappingchucktaskreasoningtechnicalgradetelangiectaticlipomatelescopicdampertemperateclimatetemperedmeasuretenementbuildingtuchkas
ultramaficrockultraviolettesting
gangwayplatformgarbagechutegardeningleavegascauterygashbucketgasreturngatedsweepgaugemodelgaussianfiltergearpitchdiametergeartreatinggeneralizedanalysisgeneralprovisions
geophysicalprobegeriatricnursegetintoaflapgetthebouncehabeascorpushabituatehackedbolthackworkerhadronicannihilationhaemagglutininhailsquallhairyspherehalforderfringe
halfsiblingshallofresidencehaltstatehandcodinghandportedheadhandradarhandsfreetelephonehangonparthaphazardwindinghardalloyteethhardasironhardenedconcreteharmonicinteraction
hartlaubgoosehatchholddownhaveafinetimehazardousatmosphereheadregulatorheartofgoldheatageingresistanceheatinggasheavydutymetalcuttingjacketedwalljapanesecedarjibtypecranejobabandonment
jobstressjogformationjointcapsulejointsealingmaterialjournallubricatorjuicecatcherjunctionofchannelsjusticiablehomicidejuxtapositiontwinkaposidiseasekeepagoodoffingkeepsmthinhandkentishglory
kerbweightkerrrotationkeymanassurancekeyserumkickplatekillthefattedcalfkilowattsecondkingweakfishkinozoneskleinbottlekneejointknifesethouseknockonatom
knowledgestatekondoferromagnetlabeledgraphlaborracketlabourearningslabourleasinglaburnumtreelacingcourselacrimalpointlactogenicfactorlacunarycoefficientladletreatedironlaggingload
laissezallerlambdatransitionlaminatedmateriallammasshootlamphouselancecorporallancingdielandingdoorlandmarksensorlandreformlanduseratiolanguagelaboratorylargeheart
lasercalibrationlaserlenslaserpulselatereventlatrinesergeantlayaboutleadcoatingleadingfirmlearningcurveleavewordmachinesensiblemagneticequatormagnetotelluricfield
mailinghousemajorconcernmammasdarlingmanagerialstaffmanipulatinghandmanualchokemedinfobooksmp3listsnameresolutionnaphtheneseriesnarrowmouthednationalcensusnaturalfunctor
navelseedneatplasternecroticcariesnegativefibrationneighbouringrightsobjectmoduleobservationballoonobstructivepatentoceanminingoctupolephononofflinesystemoffsetholderolibanumresinoid
onesticketpackedspherespagingterminalpalatinebonespalmberrypapercoatingparaconvexgroupparasolmonoplaneparkingbrakepartfamilypartialmajorantquadruplewormqualitybooster
quasimoneyquenchedsparkquodrecuperetrabbetledgeradialchaserradiationestimatorrailwaybridgerandomcolorationrapidgrowthrattlesnakemasterreachthroughregionreadingmagnifierrearchain
recessionconerecordedassignmentrectifiersubstationredemptionvaluereducingflangereferenceantigenregeneratedproteinreinvestmentplansafedrillingsagprofilesalestypeleasesamplingintervalsatellitehydrology
scarcecommodityscrapermatscrewingunitseawaterpumpsecondaryblocksecularclergyseismicefficiencyselectivediffusersemiasphalticfluxsemifinishmachiningspicetradespysalestungun
tacticaldiametertailstockcentertamecurvetapecorrectiontappingchucktaskreasoningtechnicalgradetelangiectaticlipomatelescopicdampertemperateclimatetemperedmeasuretenementbuildingtuchkas
ultramaficrockultraviolettesting
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westfal
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westfal
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теат48.5BettMONTXVIIJennПопуДостКузнстудРодиприс6480
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westfal
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lisafan
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